In their quest to try and find some sort of evolutionary similarity between humans and apes, scientists have compared DNA, proteins, anatomy, behavior, and every other conceivable feature. But many of these attempts showed that a huge chasm of dissimilarity exists with no distinct evolutionary connection. And now, a new study comparing saliva between humans and apes is once again showing the uniqueness of humans and the failure of evolutionary reasoning.1
Your saliva is a highly designed and precise combination of important proteins required for preprocessing food in your mouth prior to entering your digestive tract. Human saliva also contains other specific types of proteins needed for the maintenance of tooth mineralization and protection from microbial pathogens. The sum total of the complement of proteins in saliva is called the salivary proteome.
In a recent research study, scientists compared the salivary proteomes of humans with two ape species considered to be our closest living evolutionary relatives: chimpanzees and gorillas. They also included monkeys (Rhesus macaque) as an evolutionary out-group—an alleged distant relative.

The first major difference the researchers noted was that human saliva is much more watery and diluted than apes’ and the overall concentration of proteins is much lower. In fact, human saliva contains half the total amount of proteins compared to apes and macaques (see figure).
The next thing the scientists observed was that the concentrations of the major groups of proteins is markedly different between humans and apes as well. The researchers also noted that human-specific proteins were found that do not exist in apes. Overall, the salivary proteomes were distinctly different between not just humans and apes, but also between chimps, gorillas, and macaques.
In their conclusion, the researchers stated, “We discovered unique protein profiles in saliva of humans that were distinct from those of nonhuman primates.” They also claimed, “Certain properties and components of human and nonhuman primate saliva might have evolved in a lineage-specific manner.”1 The term “lineage specific” means there is no evolutionary overlap; each human, ape, and monkey salivary proteome is unique.
This observance doesn’t line up with evolution, but fits well with Genesis that tells us God created each type of creature after its kind.2 Humans, chimps, gorillas, and macaques are unique kinds, and both science and scripture continue to confirm this biological truth.
References
1. Thamadilok, S. et al. 2020. Human and Nonhuman Primate Lineage-Specific Footprints in the Salivary Proteome. Molecular Biology and Evolution. 37 (2): 395-405.
2. Genesis 1:21, 25
Dr. Tomkins is Life Sciences Director at the Institute for Creation Research and earned his doctorate in genetics from Clemson University.
Ape Spit Radically Different from Human
The Latest
Alive with Christ
“Now if we be dead with Christ, we believe that we shall also live with him: knowing that Christ being raised from the dead dieth no more; death...
April 2026 Wallpaper
"Ask the Lord for rain in the time of the latter rain. The Lord will make flashing clouds; He will give them showers of rain, Grass in the field...
Does Earth Have a Twin?
A possible Earth-like planet 146 light-years away has recently been discovered by citizen scientists.1 The evolutionary community is cautiously...
Giant Virus, Big Claims: Does Ushikuvirus Explain Complex Life?
A newly discovered giant virus called ushikuvirus has been described by conventional scientists as a possible clue to how complex cells evolved. But...
Conventional Science Still Struggling to Exhume the Great Unconformity
The book of Genesis tells us about a global flood that occurred about 4,500 years ago, an event that began with the bursting of the fountains of the...
Designed to Handle Oxygen: Lessons from Asgard Archaea
Oxygen gives cells energy. But oxygen can also harm cells. Any organism that uses oxygen must both harness the power and protect itself against being...
New Species of Spinosaurus Supports Flood Catastrophe
Many people are fascinated with dinosaur discoveries—a new fossil, a new species, and the impressive size. But whenever we read a news article,...
Adaptation Without Innovation: Rethinking Mutations and Design
What if mutations that seem helpful today become harmful tomorrow? That question sits at the center of a new genetics study published in Nature Ecology...
More Soft Tissue in Archaeopteryx
Was the famous extinct fossil named Archaeopteryx a bird or an evolutionary link that led to birds? And how confident should scientists and others feel...
The Lipstick Vine: Evidence of Designed Adaption
In their desire to validate the questionable case for evolution, conventional biologists will appeal to local adaptation, variation, and ecological...









