Those Amazing G Protein Receptors | The Institute for Creation Research

Those Amazing G Protein Receptors

Using freeze-fracturing and an electron microscope, researchers can indirectly view the plasma membrane of a human cell. What is revealed are large, globular protein molecules that stud the bi-lipid membrane. These proteins are designed by the Creator to receive chemical information such as hormones. One large group of these cell surface proteins is called the G protein coupled receptors (GPCRs) composed of seven membrane-spanning helices. Receptors are proteins designed to process molecular signals. GPCRs are divided into five major classes and "mediate an extraordinary spectrum of cellular processes."1 For example, they are involved with the reception of light energy packets called photons resulting in our being able to see (these are the rhodopsin-like receptors, belonging to class A of the GPCR superfamily). Over one percent of the total mammalian genes are represented by GPCRs. Hormones belong to a general group called ligands, molecules that physically bind to receptors on the plasma membrane. The G proteins (composed of three subunits) are intermediaries between these membrane-spanning receptors and effectors (designed to activate cellular processes). The receptor, effector, and G proteins are all directly associated with the plasma membrane. But how the G protein subunits are actually activated after ligands attach to the receptors forming a specific complex is not well understood.

Can Darwinists document the evolution of these amazing molecules? No. According to secular biologists the GPCRs, ligands, and effectors have been around since before the Precambrian about "600 million years ago." In other words, as far as science is concerned, these complex proteins have always been what they are today, in keeping with the creation science model.

Random genetic mistakes, or mutations, supposedly made the GPCRs, and mutations are now responsible for disease conditions involving GPCRs.

mutations in the genes encoding these receptors have been implicated in numerous diseases.2

Once again, Darwinists rely on chance genetic mistakes coupled with natural selection to produce some of the most detailed and complex biological molecules ever discovered. Either they are right or the Apostle Paul is right when he stated that God's creative power is "clearly seen" in the creation (Romans 1:20).

References

  1. Karp, G. 2002. Cell & Molecular Biology. John Wiley & Sons, p. 636.
  2. Palczewski, K. 2006. G protein-coupled receptor rhodopsin. Annual Review of Biochemistry. 75:744. (See also: Madabushi, S., et al. 2004. Evolutionary trace of GPCRs. Journal of Biol. Chem. (9):8126-32.)

*Frank Sherwin is a zoologist and seminar speaker for ICR.

Cite this article: Frank Sherwin, D.Sc. (Hon.). 2006. Those Amazing G Protein Receptors. Acts & Facts. 35 (12).

The Latest
NEWS
Aerial Engineering and Physics of the Dragonfly
Dragonflies (order Odonata) are perhaps one of the most studied and appreciated insects in the world today. Like the hummingbird, the dragonfly is a master...

NEWS
Seafloor Spreading Matches Creation Predictions
Evolutionary scientists recently determined that seafloor spreading has been slowing down.1 And they are not exactly sure of the reason. However,...

NEWS
Remembering Patti Morse
But none of these things move me; nor do I count my life dear to myself, so that I may finish my race with joy, and the ministry which I received from...

CREATION PODCAST
What Happened with Washington's Violent Volcano? | The Creation...
How did a 1980 volcanic eruption change our understanding of geology? What impact did this event have on the age assignments of sediments? Join us for...

NEWS
Fossil Insect Predation Shows No Evidence of Evolution
Some recent science news stories have come out describing fossils of insects feeding on plants supposedly many “millions of years ago.” What...

NEWS
Adaptive Genetic and Epigenetic Changes in Plants
Being sedentary organisms, plants are essentially stuck where they are planted and need to dynamically adapt to the conditions around them to not only...

NEWS
Dr. Tim Clarey Awarded Adjunct Professor of the Year
Congratulations to ICR Research Scientist and geologist Dr. Tim Clarey! He received the Adjunct Professor of the Year award from King’s University,...

NEWS
Mars Rover Records Dramatic Solar Eclipse
NASA’s Mars Perseverance rover has filmed the Martian satellite (or moon) Phobos eclipsing the sun, and this short but impressive video may be viewed...

CREATION PODCAST
Darwin or Design? CET Pt. 2 | The Creation Podcast: Episode 22
How does design provide a better explanation for biological functions and adaptations than natural selection? And how can engineering principles help...

NEWS
Resurrecting “Ancient” Enzymes?
The most abundant protein on Earth is probably an enzyme (biological catalyst) called RuBisCO (or Rubisco) designed by the Creator to function in photosynthesis.1...