Those Amazing G Protein Receptors | The Institute for Creation Research

Those Amazing G Protein Receptors

Using freeze-fracturing and an electron microscope, researchers can indirectly view the plasma membrane of a human cell. What is revealed are large, globular protein molecules that stud the bi-lipid membrane. These proteins are designed by the Creator to receive chemical information such as hormones. One large group of these cell surface proteins is called the G protein coupled receptors (GPCRs) composed of seven membrane-spanning helices. Receptors are proteins designed to process molecular signals. GPCRs are divided into five major classes and "mediate an extraordinary spectrum of cellular processes."1 For example, they are involved with the reception of light energy packets called photons resulting in our being able to see (these are the rhodopsin-like receptors, belonging to class A of the GPCR superfamily). Over one percent of the total mammalian genes are represented by GPCRs. Hormones belong to a general group called ligands, molecules that physically bind to receptors on the plasma membrane. The G proteins (composed of three subunits) are intermediaries between these membrane-spanning receptors and effectors (designed to activate cellular processes). The receptor, effector, and G proteins are all directly associated with the plasma membrane. But how the G protein subunits are actually activated after ligands attach to the receptors forming a specific complex is not well understood.

Can Darwinists document the evolution of these amazing molecules? No. According to secular biologists the GPCRs, ligands, and effectors have been around since before the Precambrian about "600 million years ago." In other words, as far as science is concerned, these complex proteins have always been what they are today, in keeping with the creation science model.

Random genetic mistakes, or mutations, supposedly made the GPCRs, and mutations are now responsible for disease conditions involving GPCRs.

mutations in the genes encoding these receptors have been implicated in numerous diseases.2

Once again, Darwinists rely on chance genetic mistakes coupled with natural selection to produce some of the most detailed and complex biological molecules ever discovered. Either they are right or the Apostle Paul is right when he stated that God's creative power is "clearly seen" in the creation (Romans 1:20).

References

  1. Karp, G. 2002. Cell & Molecular Biology. John Wiley & Sons, p. 636.
  2. Palczewski, K. 2006. G protein-coupled receptor rhodopsin. Annual Review of Biochemistry. 75:744. (See also: Madabushi, S., et al. 2004. Evolutionary trace of GPCRs. Journal of Biol. Chem. (9):8126-32.)

*Frank Sherwin is a zoologist and seminar speaker for ICR.

Cite this article: Frank Sherwin, M.A. 2006. Those Amazing G Protein Receptors. Acts & Facts. 35 (12).

The Latest
NEWS
Origin of Tectonic Plates Best Explained by the Flood
A new study published in Nature Communications claims to have figured out how the tectonic plates may have originated.1 It’s been over...

NEWS
Give Today and Support Biblical Creation Ministry
North Texas Giving Day is here once again! Will you help us reach the next generation? Your generosity will empower ICR and our Dallas Museum—the...

NEWS
Mammalian Brains Prove Evolutionary Disconnect
The evolutionary model of brain development predicted that the complexity of neural connectivity should have increased as brains became larger and the...

NEWS
North Texas Giving Day Next Week!
North Texas Giving Day is almost here! Will you help us reach the next generation? Your generosity will empower ICR and the ICR Discovery Center for Science...

NEWS
Celebrating One Year at the ICR Discovery Center
Thank you to all who joined us for the ICR Discovery Center for Science & Earth History’s First Anniversary Celebration! ICR staff enjoyed meeting...

NEWS
New Evidence Hurts Feathered Dinosaur Theory
Is a dinosaur still a dinosaur if it has flight feathers? A new study points to some fascinating evidence that contradicts the idea of feathered dinosaurs...

NEWS
New Planetarium Show: Exploring Deep Space
The ICR Discovery Center for Science & Earth History is celebrating its first anniversary since the Grand Opening on September 2, 2019. To commemorate...

NEWS
Inside September 2020 Acts & Facts
What's the story behind ICR's new President? What milestone are we celebrating this month at the ICR Discovery Center? How do comets affirm...

NEWS
Sunflower Heliotropism: August Sunlight for Making Tons of Seeds
August is an important month for sunflowers—those gigantic, bright-yellow flowers with brownish, round seed heads bordered by radiating yellow ligules...

ACTS & FACTS
One Generation Away
In 1967, Ronald Reagan delivered one of the most memorable lines of his storied career: “Freedom…is never more than one generation away...