Those Amazing G Protein Receptors | The Institute for Creation Research

Those Amazing G Protein Receptors

Using freeze-fracturing and an electron microscope, researchers can indirectly view the plasma membrane of a human cell. What is revealed are large, globular protein molecules that stud the bi-lipid membrane. These proteins are designed by the Creator to receive chemical information such as hormones. One large group of these cell surface proteins is called the G protein coupled receptors (GPCRs) composed of seven membrane-spanning helices. Receptors are proteins designed to process molecular signals. GPCRs are divided into five major classes and "mediate an extraordinary spectrum of cellular processes."1 For example, they are involved with the reception of light energy packets called photons resulting in our being able to see (these are the rhodopsin-like receptors, belonging to class A of the GPCR superfamily). Over one percent of the total mammalian genes are represented by GPCRs. Hormones belong to a general group called ligands, molecules that physically bind to receptors on the plasma membrane. The G proteins (composed of three subunits) are intermediaries between these membrane-spanning receptors and effectors (designed to activate cellular processes). The receptor, effector, and G proteins are all directly associated with the plasma membrane. But how the G protein subunits are actually activated after ligands attach to the receptors forming a specific complex is not well understood.

Can Darwinists document the evolution of these amazing molecules? No. According to secular biologists the GPCRs, ligands, and effectors have been around since before the Precambrian about "600 million years ago." In other words, as far as science is concerned, these complex proteins have always been what they are today, in keeping with the creation science model.

Random genetic mistakes, or mutations, supposedly made the GPCRs, and mutations are now responsible for disease conditions involving GPCRs.

mutations in the genes encoding these receptors have been implicated in numerous diseases.2

Once again, Darwinists rely on chance genetic mistakes coupled with natural selection to produce some of the most detailed and complex biological molecules ever discovered. Either they are right or the Apostle Paul is right when he stated that God's creative power is "clearly seen" in the creation (Romans 1:20).

References

  1. Karp, G. 2002. Cell & Molecular Biology. John Wiley & Sons, p. 636.
  2. Palczewski, K. 2006. G protein-coupled receptor rhodopsin. Annual Review of Biochemistry. 75:744. (See also: Madabushi, S., et al. 2004. Evolutionary trace of GPCRs. Journal of Biol. Chem. (9):8126-32.)

*Frank Sherwin is a zoologist and seminar speaker for ICR.

Cite this article: Frank Sherwin, D.Sc. (Hon.). 2006. Those Amazing G Protein Receptors. Acts & Facts. 35 (12).

The Latest
NEWS
Inside December 2021 Acts & Facts
How can we understand Christ’s role as our mediator from a scientific perspective? Why was ICR's first dinosaur excavation significant for...

APOLOGETICS
Christ’s Providence Is Clearly Seen in Bird Migrations
Just as monkeys can’t accidently type Shakespeare texts, birds can’t migrate by evolutionary luck, despite imagined eons of time for “lucky”...

ACTS & FACTS
Creation Kids: Snowflakes
by Christy Hardy and Susan Windsor* You’re never too young to be a creation scientist! Kids, discover fun facts about God’s creation with...

ACTS & FACTS
The Gift of God Himself
Each Christmas we remember how deeply God loves us. His wondrous plan of salvation—first set in motion in the Garden of Eden—was miraculously...

ACTS & FACTS
Early Land Plant Evolution?
In a recent Science article, two evolutionists consider land plants (embryophytes) to have evolved from stoneworts (charophyte algae).1 A...

ACTS & FACTS
Biblical Creation and Intellectual Foolishness
In a recent interview discussing his new book In Quest of the Historical Adam, philosopher and Christian apologist William Lane Craig acknowledged his...

ACTS & FACTS
Are Birds “Cousins” to Reptiles?
Are today’s birds genealogical “cousins” to today’s reptiles due to a shared evolutionary ancestry? No. However, birds and...

ACTS & FACTS
Haleakala National Park: One of Many Young-Looking Volcanoes
You can start the day atop the cold peak of Mt. Haleakala and end it on a warm beach on Maui. The sprawling volcanic mountain rises 10,000 feet above...

ACTS & FACTS
The Oceans Point to a Young Earth
by Jeffrey P. Tomkins, Ph.D., and Tim Clarey, Ph.D.* Over 70% of Earth's surface is covered by water, most of which is marine and contained in...

ACTS & FACTS
Jesus Christ Is Our Perfect Mediator
We’ll never get bored throughout eternity. There is always something wonderfully new to learn about our precious Lord Jesus, the uplifting Holy...