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Woe unto them that call evil good, and good evil; that put darkness for light, and light for darkness; that put bitter for sweet, and sweet for bitter!
Woe unto them that are wise in their own eyes, and prudent in their own sight!
Woe unto them that are mighty to drink wine, and men of strength to mingle strong drink:
Which justify the wicked for reward, and take away the righteousness of the righteous from him!
Therefore as the fire devoureth the stubble, and the flame ° consumeth the chaff, so their root shall be as rottenness, and their blossom shall go up as dust: because they have cast away the law of the LORD of hosts, and despised the word of the Holy One of Israel.

New Defender's Study Bible Notes

5:20 Woe. Six woes are pronounced on Judah in this section (Isaiah 5:8,11,18,20,21,22).

5:20 call evil good. Inversion of God’s standards of right and wrong characterizes times of apostasy and precedes times of divine judgment. This phenomenon is increasingly characteristic of Christendom today.

5:21 in their own eyes. It is typical of evolutionary pantheism, both ancient and modern, that men will be “professing themselves to be wise,” while becoming “fools” (Romans 1:22).

5:22 drink wine. This is one of many Scriptures that warns against strong drink.

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