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Woe unto them that call evil good, and good evil; that put darkness for light, and light for darkness; that put bitter for sweet, and sweet for bitter!
Woe unto them that are wise in their own eyes, and prudent in their own sight!

New Defender's Study Bible Notes

5:20 Woe. Six woes are pronounced on Judah in this section (Isaiah 5:8,11,18,20,21,22).

5:20 call evil good. Inversion of God’s standards of right and wrong characterizes times of apostasy and precedes times of divine judgment. This phenomenon is increasingly characteristic of Christendom today.

5:21 in their own eyes. It is typical of evolutionary pantheism, both ancient and modern, that men will be “professing themselves to be wise,” while becoming “fools” (Romans 1:22).

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