New Defender's Study Bible Notes
11:19 Antioch. Antioch was the capital of Syria, and in the Roman Empire only Rome and Alexandria were larger. It was a very busy and beautiful city, located on the river Orontes. It was also cosmopolitan and very immoral. With a large colony of Jews, it was natural that many of the scattering Hellenistic Jews would come there, arriving by water first from the Phoenician coastlands as they traveled north, with some turning aside to sail to the isle of Cyprus. The preaching of these Hellenistic Jews from Jerusalem soon resulted in the conversion of many Jews in the synagogues at Antioch, and the establishment of a church at Antioch.