The Human GULO Pseudogene—Evidence for Evolutionary Discontinuity and Genetic Entropy | The Institute for Creation Research
 
The Human GULO Pseudogene—Evidence for Evolutionary Discontinuity and Genetic Entropy

In Answers Research Journal 7 (2014): 91-101

Modern genomics provides the ability to screen the DNA of a wide variety of organisms to scrutinize broken metabolic pathways. This wealth of data has revealed wide-spread genetic entropy in human and other genomes. Loss of the vitamin C pathway due to deletions in the GULO (L-gulonolactone oxidase) gene has been detected in humans, apes, guinea pigs, bats, mice, rats, pigs, and passerine birds. Contrary to the popularized claims of some evolutionists and neo-creationists, patterns of GULO degradation are taxonomically restricted and fail to support macroevolution. Current research and data reported here show that multiple GULO exon losses in human, chimpanzee, and gorilla occurred independently in each taxon and are associated with regions containing a wide variety of transposable element fragments. Thus, they are another example of sequence deletions occurring via unequal recombination associated with transposable element repeats. The 28,800 base human GULO region is only 84% and 87% identical compared to chimpanzee and gorilla, respectively. The 13,000 bases preceding the human GULO gene, which corresponds to the putative area of loss for at least two major exons, is only 68% and 73% identical to chimpanzee and gorilla, respectively. These DNA similarities are inconsistent with predictions of the common ancestry paradigm. Further, gorilla is considerably more similar to human in this region than chimpanzee—negating the inferred order of phylogeny. Taxonomically restricted gene degradation events are emerging as a common theme associated with genetic entropy and systematic discontinuity, not macroevolution.

Click here to read the full article text.

The Latest
NEWS
Another Sea Scorpion
There are few animals more nightmarish than an 8-foot sea scorpion! Although, they were not true scorpions, their fossils display a menacing and formidable...

NEWS
June 2023 ICR Wallpaper
"From the rising of the sun to its going down the LORD's name is to be praised." Psalm 113:3 NKJV ICR June 2023 wallpaper is now available...

NEWS
Sauron Inhabits the Amazon
“The Eye was rimmed with fire, but was itself glazed, yellow as a cat’s, watchful and intent, and the black slit of its pupil opened on...

DAYS OF PRAISE DEVOTIONALS
Summer 2023
...

CREATION PODCAST
I Have NO Credentials! | The Creation Podcast: Episode 50
Do you need a science degree to be a champion of creation? How do we communicate the truths of Scripture to our friends and family? The good news...

NEWS
Shark Jaws
Sharks are back in the news, and it’s in regard to their most formidable and fearsome structure—their jaws. Zoologists recently studied...

CREATION.LIVE PODCAST
Established Day 4 | Creation.Live Podcast: Episode 13
Humans have long been fascinated by the night sky. As Psalm 19:1 reminds us, "The heavens declare the glory of God"—His creative signature...

NEWS
Physical Evidence Trumps Evolution Theory
One of the hallmarks of good science is to formulate a cogent theory based on the physical evidence. For example, if the physical evidence (e.g. a fossilized...

NEWS
Solar System Symmetries
Most all school children can recite the planets in our solar system using memory devices such as: “My Very Easy Method Just Speeds Up Names”...

NEWS
Does Iron Toast Union Rescue Long Ages?
The puzzle persists after all these years. On the one hand, biochemists perform decay rate studies that show biochemicals cannot last a million years...