Comprehensive Analysis of Chimpanzee and Human Chromosomes Reveals Average DNA Similarity of 70% | The Institute for Creation Research
 
Comprehensive Analysis of Chimpanzee and Human Chromosomes Reveals Average DNA Similarity of 70%

In Answers Research Journal 6 (2013): 63-69

Since the original 2005 report for the chimpanzee (chimp) genome assembly (5X rough draft), an additional one-fold redundant coverage has been added. Using the new 6X chimpanzee assembly, a sequential comparison to the human genome was performed on an individual chromosome basis. The chimpanzee chromosomes, were sliced into new individual query files of varying string lengths and then queried against their human chromosome homolog using the BLASTN algorithm. Using this approach, queries could be optimized for each chromosome irrespective of gene/feature linear order. Non-DNA letters (gap filling ‘N’s) were stripped from the query data and excluded from the analyses. The definition of similarity for each chromosome was the amount (percent) of optimally aligned chimp DNA. This definition was considered to be conservative because it did not include the amount of human DNA absent in chimp nor did it include chimp DNA that was not aligned to the human genome assembly (unanchored sequence contigs). For the chimp autosomes, the amount of optimally aligned DNA sequence provided similarities between 66 and 76%, depending on the chromosome. In general, the smaller and more gene-dense the chromosomes, the higher the DNA similarity—although there were several notable exceptions defying this trend. Only 69% of the chimpanzee X chromosome was similar to human and only 43% of the Y chromosome. Genome-wide, only 70% of the chimpanzee DNA was similar to human under the most optimal sequence-slice conditions. While, chimpanzees and humans share many localized protein-coding regions of high similarity, the overall extreme discontinuity between the two genomes defies evolutionary timescales and dogmatic presuppositions about a common ancestor.

Click here to read the full article text.

The Latest
CREATION PODCAST
Why Do Animals Hibernate? | The Creation Podcast: Episode 45
The word hibernation is often used in reference to deep sleep, but what is it really? What kinds of creatures hibernate? How does this demonstrate the...

NEWS
Thalattosuchians—Extinct Crocodile Relatives?
The Thalattosuchia are an extinct group of marine crocodylomorphs (a group that includes the crocodiles) that allegedly transitioned from land to water...

NEWS
The Star-Nosed Mole
The star-nosed mole (Condylura cristata) is a fascinating semi-aquatic mammal found in eastern Canada and the United States. Moles (placental mammals)...

NEWS
The Hexagon: An Indication of Order and Design in Nature
In nature, noncoincidental patterns and geometry exist everywhere. But the number six appears to overshadow nature’s mathematical landscape. Whether...

NEWS
Neanderthal Crab Bake
The evolutionary science community said it perfectly in their headlines: “Proof that Neanderthals ate crabs is another 'nail in the coffin'...

CREATION PODCAST
Is There Any Truth to Dragon Legends? | The Creation Podcast:...
Dragons are considered by many to be made-up creatures in fairytales and legends, but our ancestors produced many descriptions and depictions of "dragons,"...

NEWS
Our Sun, Finely Tuned for Life on Earth
Aside from appreciating the splendor of the sun during a beautiful sunrise or sunset, many rarely consider how special, necessary, and finely tuned...

NEWS
March 2023 ICR Wallpaper
"Sing to the Lord with thanksgiving; Sing praises on the harp to our God, Who covers the heavens with clouds, Who prepares rain for the earth, Who...

ACTS & FACTS
Creation Kids: Auroras
by Lori Fausak and Susan Windsor* You’re never too young to be a creation scientist! Kids, discover fun facts about God’s creation...

ACTS & FACTS
Meet ICR's Donor Relations Department
Meet our Donor Relations team led by Director Charles (Chas) Morse. Their objective is to transform donated resources into Scripture-affirming science...