"For they being ignorant of God's righteousness, and going about to establish their own righteousness, have not submitted themselves unto the righteousness of God." (Romans 10:3)
There are several important doctrinal truths about which unbelievers--and sometimes even Christians--seem tragically ignorant, with an ignorance affecting their very lives and destinies. Perhaps the most tragic is that mentioned in our text. Paul was writing specifically of the Jews, but the same ignorance is found in countless others--people who seek to earn salvation by their own religious and moral works rather than through faith in the imputed righteousness of Christ, who died for their sins.
There is also widespread ignorance concerning death and life beyond the grave. "I would not have you to be ignorant, brethren, concerning them which are asleep, that ye sorrow not, even as others which have no hope. For if we believe that Jesus died and rose again, even so them also which sleep in Jesus will God bring with him" (1 Thessalonians 4:13-14). With respect to Christian life and ministry, Paul says: "Now concerning spiritual gifts, brethren, I would not have you ignorant" (1 Corinthians 12:1). Yet most Christians neglect to develop or use their gifts, mainly because of ignorance concerning their proper function as described in 1 Corinthians 12, 14; Romans 12:3-21; Ephesians 4:7-16, and other key passages.
We urgently also need to be instructed concerning the deceptions of the wicked one: "Lest Satan should get an advantage of us: for we are not ignorant of his devices" (2 Corinthians 2:11). For all who seek instruction rather than ignorance, let them study God's word, for "all scripture . . . is profitable for . . . instruction in righteousness" (2 Timothy 3:16). HMM