New Defender's Study Bible Notes
2:13 ordinance of man. The phrase “ordinance of man” means, literally, “human creation.” Since only God really creates, we must regard human ordinances as divine ordinances and submit to them as unto God, unless they contradict God’s written Word. Note Romans 13:1.
2:15 ignorance. The Greek word here for “ignorance” is agnosia, from which we get our word “agnostic.”