5:22 walked with God. Enoch presumably did not literally walk with God, as had Adam before the fall, but walked “by faith” (Hebrews 11:5) in prayer and obedience to God’s Word. There seems to be an implication that this spiritual walk had a special beginning at the time of his son’s birth, and the accompanying revelation. Note also Genesis 6:9.
5:22 sons and daughters. It is worth noting that Enoch’s walk with God was not such a mystical, pietistic experience as to preclude an effective family life or a strong and vocal opposition to the apostasy and wickedness of his day (Jude 14,15).