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New Defender's Study Bible Notes
2:22 great tribulation. Christ referred to a coming period of “great tribulation,” and so did “one of the elders” later speaking to John (Matthew 24:21; Revelation 7:13-14). This warning indicates that the adulterous members (spiritually adulterous, as well as physically, and thus not truly born-again believers) of those Thyatira-like churches at the end of the age will be left behind when Christ returns and be cast into the period of great tribulation on earth, unlike the church at Philadelphia (see note on Revelation 3:10).