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In the same hour came forth fingers of a man's hand, and wrote over against the candlestick upon the plaster of the wall of the king's palace: and the king saw the part of the hand that wrote.
Then the king's countenance was changed, and his thoughts troubled him, so that the joints of his loins were loosed, and his knees smote one against another.

New Defender's Study Bible Notes

5:5 man’s hand. This was probably an angel sent from God with His message of judgment. Angels can appear as men (e.g., Genesis 19:1, 15-16), so undoubtedly can materialize as any part of a man’s body.

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