New Defender's Study Bible Notes
21:6 wizards. Manasseh, despite his godly father, soon took up the abominable practices of his grandfather Ahaz and the kings of Israel (II Kings 16:3; 17:17). His father died when he was only twelve years old (II Kings 21:1) and evidently had devoted little time to Manasseh’s religious instruction. Nothing is known about his mother except her name, which means “My delight is in her,” a name perhaps indicating over-indulgent parents.”
21:6 much wickedness. Manasseh shed much “innocent blood” (II Kings 21:16) and, according to Jewish tradition, this may even have included the prophet Isaiah, who was supposed to have been “sawn asunder” (Hebrews 11:37).