Genetic Expression: Same Genes Can Produce Different Results | The Institute for Creation Research
Genetic Expression: Same Genes Can Produce Different Results

Genes could be thought of as brick molds, used to construct materials for building the physical structures of living organisms. They carry the codes to help make proteins, which then make up different cells that are combined together to form mega-structures called tissues. New research has shed more light on how genes are used by cells to build the different tissues needed by complex living creatures.

Genes—which make up a very small fraction of DNA—were thought to be the central genetic features that drive cell function and embryonic development. New evidence shows that non-gene DNA is almost fully used in cells, and that there is coded information (but not genes) in the cell that manages which genes are expressed, when, and how often.1

In 2005, a landmark study found that certain very similar human and chimpanzee genes differ in sequence by an average of 4.4 percent.2 Evolutionary scientists believe that the percentage of shared gene sequences between chimps and people supports the hypothesis that they have a common biological ancestor.

But in a recent study published in the November 11, 2008, issue of Developmental Cell, researchers discovered that when different tissues within kidneys are formed in the womb, the dividing cells do not use different genes to produce the distinct building “bricks” that are needed for each kind of tissue!3 Lead author Eric Brunskill summarized that “almost all of the genes are expressed in the different parts but at varied levels.”4

Thus, the same genes were used to make quite different structures. As an example, bricks that come from the same mold may be similar or even identical, but they can be variously arranged to build a house, a patio, or a sidewalk. Likewise, even if certain genes are identical between two kinds of creatures—i.e., humans and chimps—it’s the expression and arrangement of those gene products that determine what tissues are produced.

Since different features can be built using the same genes, some of the similarities between chimp and human genes carry less relevance for an evolutionary interpretation of origins. The assumption that people are evolutionary relatives of chimps because they share similar genes is invalid for at least two reasons. First, even though research has found that a 4.4 percent average difference in sequence exists between the similar genes, there are in fact many distinct genes that humans have and chimps do not, and vice versa. Second, there is a large percentage of the two separate genomes that have not yet been correlated, and it is likely that significant non-gene sequence differences will become known—just as one recent study discovered.5

Even with the same or almost the same genes, many differences between apes and humans exist because the genes are “unpacked” differently during development. To make the story of human evolution plausible, its proponents need to demonstrate not only a natural mechanism that generates new complete genes from scratch, but another natural mechanism that generates the precise and effective gene unfolding programs that are known to produce distinct cells, tissues, organs, and organisms.

References

  1. The Chimpanzee Sequencing and Analysis Consortium. 2005. Initial sequence of the chimpanzee genome and comparison with the human genome. Nature. 437 (7055): 77.
  2. Brunskill, E. W. et al. 2008. Atlas of Gene Expression in the Developing Kidney at Microanatomic Resolution. Developmental Cell. 15 (5): 781-791.
  3. Genetic Blueprint Revealed for Kidney Design and Formation. Cincinnati Children’s Hospital Medical Center press release, November 10, 2008.
  4. Perry, G. H. et al. 2008. Copy Number Variation and Evolution in Humans and Chimpanzees. Genome Research. 18 (11): 1703.

* Mr. Thomas is Science Writer.

Article posted on November 19, 2008.

The Latest
NEWS
ICR’s 2021 Science Expedition Update–Dinosaur Fossils
A team of 11 people from the Institute for Creation Research is currently traveling on a multistate science expedition to dig up fossils, conduct field...

NEWS
ICR’s 2021 Science Expedition Update
A team of 11 people from the Institute for Creation Research is currently traveling on a multistate science expedition to dig up fossils, conduct field...

NEWS
ICR’s 2021 Science Expedition Begins!
The Institute for Creation Research launched its 2021 multistate science expedition last week as a nine-member team left the ICR headquarters in Dallas,...

NEWS
Inside September 2021 Acts & Facts
Why does ICR focus on scientific research? How could paleontologists mistake a lizard fossil for a dinosaur? Is animal death before the Fall theologically...

ACTS & FACTS
Creation Kids: Beauty by Design
Christy Hardy and Susan Windsor* You’re never too young to be a creation scientist! Kids, discover fun facts about God’s creation with...

ACTS & FACTS
Defend Your Faith with ICR
Have you ever heard a pastor question the historical nature of Genesis? “The days of creation weren’t really 24 hours long. The Bible is...

ACTS & FACTS
Animal Death Before the Fall?
Both the Old and New Testaments teach that death entered the world when Adam ate the forbidden fruit (e.g., Genesis 2:17 and Romans 5:12). Since fossils...

APOLOGETICS
Transmitting Truth in a Modern Pagan World
We share the world with modern pagans who worship the sun—or idolize an imagined primordial Big Bang—so we need to be truth witnesses unto...

ACTS & FACTS
Waco Mammoth National Monument
Hunters in the 1970s discovered mammoth bones exposed in sediments near the confluence of the Bosque and Brazos Rivers in north central Texas. They...

ACTS & FACTS
Three Hurdles for Evolution
Sure, finch beaks shift their shapes, but does that mean nature invented beaks and birds from stardust? Evolution’s proponents often speak as...