New Defender's Study Bible Notes
14:25 Assyrian. See Isaiah 10:5; Micah 5:5-6. The Assyrians were even more imminent a danger than the Babylonians. This prophecy also has a near and distant fulfillment, with “the Assyrian” being a title of the future Antichrist.
14:25 tread him under foot. This may well be a reference to the primeval promise of Genesis 3:15, with the Antichrist possessed by Satan, like the king of Babylon.