21:4 all tears. Note Isaiah 25:8-9 and Revelation 7:17. Our tears of sorrow will in that day be turned into tears of joy and thanksgiving.

21:4 any more pain. The four aspects of the primeval curse of Genesis 3:17-19 (sweat, sorrow, pain and death) are specifically removed when God wipes away our tears. This is possible only because the Lord Jesus Christ was made the curse for us (Galatians 3:13). He “in an agony…sweat as it were great drops of blood” as He “carried our sorrows,” then was painfully “wounded for our transgressions” and “bruised for our iniquities.” Finally, He “poured out His soul unto death” (Luke 22:44; Isaiah 53:4-5,12). As the physical aspects of the curse had already been purged (II Peter 3:10), so also will its entire profound spiritual aspects, and “there shall be no more curse” (Revelation 22:3).

21:25 no night there. Although there will be no “night” in the city itself, there will continue to be day and night in the cosmos as a whole (e.g., Revelation 20:10), as well as “months” on the new earth (Revelation 22:2).