6:1 the Lord. Adonai is the divine name of God as seen in Isaiah’s vision (Isaiah 6:8,11). However, the Seraphim call Him Jehovah Sabaoth meaning “LORD of hosts” (Isaiah 6:3).
6:2 seraphims. This is the only reference in the Bible to these angelic beings, perhaps similar in rank to the cherubim, yet different in function. The name, seraphim, literally means “burners.” It is barely possible that these are the same as the cherubim.
6:3 Holy, holy, holy. The threefold ascription of holiness to the One on the throne suggests His tri-unity.
6:5 Woe is me. Isaiah had pronounced six “woes” on the people of Israel because of their sins, and justifiably so. However, when confronted with the glory and holiness of God, he must also cry: “Woe is me”—apart from the grace of God.
6:5 mine eyes have seen. Isaiah saw the Second Person of the divine Triune Godhead (John 1:18). He indeed is “the King, the LORD of hosts.”
6:9 he said. The commission given to Isaiah in Isaiah 6:9-10 is quoted by Christ (Matthew 13:13-14) as a rebuke to the religionists of His own day, who were making an outward show of religion, but had no real understanding of God and His will.
6:12 removed men far away. This prophetic warning was given some 150 years in advance of its fulfillment. The Lord always fulfills His Word, even though it may be long in coming.
6:13 it shall return. This is a reference to the “remnant,” the godly minority who would return to their land after the exile.