2:10 hide thee in the dust. The prophecies of Isaiah 2:10-22 will be fulfilled in their ultimate sense in the coming great tribulation period of the end-times. Note the context (Isaiah 2:12).
2:12 the day of the LORD. This is the first, and thus definitive use of the prophetic phrase, “the day of the LORD” in the Bible. The phrase often applies precursively to an imminent judgment of God (as in Isaiah 3:1), but primarily and ultimately to the time of the great tribulation.
2:19 shake terribly the earth. While the first nine verses of this chapter focus on the sins of Judah and Jerusalem (Isaiah 2:1), the coming judgment on the Holy Land is only a type of the judgment on the whole world in the last days, and the remainder of the chapter leaps ahead to a vision of this great end-time judgment. Compare the same scene in Revelation 6:15-17.