2:3 In whom. Since Christ is the Creator and Sustainer of all things (Colossians 1:16, 17), and since His gospel is implicit in every thing created (Colossians 1:23), it follows that true science is essentially thinking God’s thoughts after Him. All the treasures of true wisdom and knowledge are stored up in Christ (Matthew 13:52), and all education should be Christ-centered.
2:3 wisdom. False wisdom (i.e., “philosophy”—see Colossians 2:8) was the device used by Satan to tempt Eve (Genesis 3:6), and false knowledge (i.e., “false science”—see I Timothy 6:20) was the corrupt fruit which brought death into the world (Genesis 2:17; 3:17-19).
2:3 knowledge. “Knowledge” is synonymous with “science,” both being translations of the Greek gnosis. “The fear of the Lord is the beginning” of both true wisdom and true knowledge (Proverbs 1:7; 9:10).
2:6 As ye have. That is, we have received Christ by faith; therefore we should also walk by faith in him, trusting Him for all needed provision and guidance.
2:6 so walk. The Christian “walk” should be in His light (John 8:12), in wisdom (Colossians 4:5), in circumspection (Ephesians 5:15), in newness of life (Romans 6:4), by faith (II Corinthians 5:7), honestly (I Thessalonians 4:12), and in the Spirit (Galatians 5:16).

